AIM: The aim of this systematic literature review was to identify the extent and implications of medication loss and the burden of prescription refill on medical relief teams following extreme weather events and other natural hazards.

METHOD: The search strategy followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Key health journal databases (Medline, Embase, PsycINFO, Maternity and Infant Care, and Health Management Information Consortium (HMIC)) were searched via the OvidSP search engine. Search terms were identified by consulting MeSH terms. The inclusion criteria comprised articles published from January 2003 to August 2013, written in English and containing an abstract. The exclusion criteria included abstracts for conferences or dissertations, book chapters and articles written in a language other than English. A total of 70 articles which fulfilled the inclusion criteria were included in this systematic review.

RESULTS: All relevant information was collated regarding medication loss, prescription loss and refills, and medical aids loss which indicated a significant burden on the medical relief teams. Data also showed the difficulty in filling prescriptions due to lack of information from the evacuees. People with chronic conditions are most at risk when their medication is not available. This systematic review also showed that medical aids such as eye glasses, hearing aids as well as dental treatment are a high necessity among evacuees.

DISCUSSION: This systematic review revealed that a considerable number of patients lose their medication during evacuation, many lose essential medical aids such as insulin pens and many do not bring prescriptions with them when evacuated.. Since medication loss is partly a responsibility of evacuees, understanding the impact of medication loss may lead to raising awareness and better preparations among the patients and health care professionals. People who are not prepared could have worse outcomes and many risk dying when their medication is not available.

Background
Extreme events (e.g. flooding) threaten critical infrastructure including power supplies. Many interlinked systems in the modern world depend on a reliable power supply to function effectively. The health sector is no exception, but the impact of power outages on health is poorly understood. Greater understanding is essential so that adverse health impacts can be prevented and/or mitigated.

Methods
We searched Medline, CINAHL and Scopus for papers about the health impacts of power outages during extreme events published in 2011-2012. A thematic analysis was undertaken on the extracted information. The Public Health England Extreme Events Bulletins between 01/01/2013 – 31/03/2013 were used to identify extreme events that led to power outages during this three-month period.

Results
We identified 20 relevant articles. Power outages were found to impact health at many levels within diverse settings. Recurrent themes included the difficulties of accessing healthcare, maintaining frontline services and the challenges of community healthcare. We identified 52 power outages in 19 countries that were the direct consequence of extreme events during the first three months of 2013.

Conclusions
To our knowledge, this is the first review of the health impacts of power outages. We found the current evidence and knowledge base to be poor. With scientific consensus predicting an increase in the frequency and magnitude of extreme events due to climate change, the gaps in knowledge need to be addressed in order to mitigate the impact of power outages on global health.